By Lodovico Balducci, William B. Ershler, John M. Bennett

ISBN-10: 0387495053

ISBN-13: 9780387495057

ISBN-10: 0387495061

ISBN-13: 9780387495064

Anemia within the aged has been adequately outlined because the silent epidemic, representing three million humans within the usa elderly sixty five years and older. prevalence and incidence of this elevate with age. It differs in its etiology, pathogenesis and therapy from anemia in kids and more youthful adults. Anemia is linked to diminished survival, elevated probability of sensible dependence and hospitalization, elevated chance of congestive middle failure and degree renal disorder and cognitive problems. nearly 70% of anemia in older participants is reversible.

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Blood. 2004 Oct 15;104(8):2263–8 7. Beghe C, Wilson A, Ershler WB: Prevalence and outcomes of anemia in geriatrics: a systematic review of the literature. Am J Med. 2004 Apr 5;116 Suppl 7A:3S–10S 8. Anι´a BJ, Suman VJ, Fairbanks VF, Rademacher DM, Melton LJ 3rd: Incidence of anemia in older people: an epidemiologic study in a well defined population. J Am Geriatr Soc. 1997 Jul;45:825–31 9. Lipsitz LA: Physiological complexity, aging, and the path to frailty. Sci Aging Knowledge Environ. 2004 Apr 21;2004(16):pe16.

According to a recent study anemia was also associated with increased risk of falls, both in institutions and in the community (67). Falls are a geriatric syndrome, associated with increased mortality and morbidity, including hip fractures. At this point it should be emphasized that currently there is no proof that correction of mild anemia in older patients will avert the complications of anemia. Anemia of a specific cause of course should be corrected. Correction of ACI with erythropoietic growth factors improves the fatigue of cancer patients, but so far no other benefits of this approach have been demonstrated (68).

2006;166:1380–8 43. List A, Dewald G, Bennett J et al: Lenalidomide in the myelodysplastic syndrome with chromosome 5q deletion. N Engl J Med. 2006 Oct 5;355(14):1456–65 44. Kikuchi M, Inagaki T, Shinagawa N: Five-year survival of older people with anemia: variation with hemoglobin concentration. J Am Ger Soc. 2001;49:1226–8 45. Izaks GJ, Westendorp RGJ, Knook DL: The definition of anemia in older persons. JAMA. 1999;281(18):1714–1719 46. Penninx BW, Pahor M, Woodman RC et al: Anemia in old age is associated with increased mortality and hospitalization.

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Anemia in the Elderly by Lodovico Balducci, William B. Ershler, John M. Bennett

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