By Wolfgang Schaper, Jutta Schaper
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MUNOZ-CHAPULI R‚ GONZALEZ-IRIARTE M‚ CARMONA R‚ ATENCIA G‚ MACIAS D‚ PEREZPOMARES JM. Cellular precursors of the coronary arteries. Tex Heart Inst J. 2002;29:243-9. 46. ORKIN SH. Stem cell alchemy. Nature Medicine. 2000;6:1212-1213. 47. LAFLAMME MA‚ MYERSON D‚ SAFFITZ JE‚ MURRY CE. Evidence for cardiomyocyte repopulation by extracardiac progenitors in transplanted human hearts. Circ Res. 2002;90:634-40. Structural Remodeling during Growth of Collateral Vessels 51 48. AVOLIO A, JONES D, M. T-S. Quantification of alterations in structure and function of elastin in the arterial media.
Penetration of the endothelial layer; 3. Infiltration of the neointima and media. In the first stage‚ mononuclear cells can be clearly identified as blood borne monocytes (Fig. 4a) but while they are immigrating the vessel wall they seem to alter their phenotype. They enlarge and the nucleus becomes more oval than horseshoe shaped but they still contain their dense granules and subcellular organelles are sparse‚ which identifies these cells to be monocytes (Fig. 4b). Occasionally‚ the immigrated non-muscle cells contain only a small cytoplasmic body‚ and the nucleus shows a chromatin distribution characteristic of lymphocytes (Fig.
Anat Rec. 1993;235:95-110. 23. LI Z‚ MARCHAND P‚ HUMBERT J‚ BABINET C‚ PAULIN D. Desmin sequence elements regulating skeletal muscle-specific expression in transgenic mice. Development. 1993;117:947-59. 24. LI Z‚ MERICSKAY M‚ AGBULUT O‚ BUTLER-BROWNE G‚ CARLSSON L‚ THORNELL L-E‚ BABINET C‚ PAULIN D. Desmin is essential for the tensile strength and integrity of myofibrils but not for myogenic commitment‚ differentiation‚ and fusion of skeletal muscle. J Cell Biol. 1997;139:129-144. 25. AGBULUT O‚ LI Z‚ PERIE S‚ LUDOSKY MA‚ PAULIN D‚ CARTAUD J‚ BUTLER-BROWNE G.
Arteriogenesis by Wolfgang Schaper, Jutta Schaper